mice
Gene loss creates eating disorder-related behaviors in mice
Building on their discovery of a gene linked to eating disorders in humans, a team of researchers at the University of Iowa has now shown that loss of the gene in mice leads to several behavioral abnormalities that resemble behaviors seen in people with anorexia nervosa. The team, led by Michael Lutter, MD, PhD, assistant […]
Immune cells in brain respond to fat in diet, causing mice to eat
Immune cells perform a previously unsuspected role in the brain that may contribute to obesity, according to a new study by UC San Francisco researchers. When the researchers fed mice a diet high in saturated milk fats, microglia, a type of immune cell, underwent a population explosion in the brain region called the hypothalamus, which […]
Another case against the midnight snack: Researchers tinker with a time-restricted diet in mice and find that it’s remarkably forgiving
These days, with the abundance of artificial light, TV, tablets and smartphones, adults and children alike are burning the midnight oil. What they are not burning is calories: with later bedtimes comes the tendency to eat. A new study by researchers at the Salk Institute cautions against an extended period of snacking, suggesting instead that […]
Derivative of vitamin B3 prevents liver cancer in mice
Liver cancer is one of the most frequent cancers in the world, and with the worst prognosis; according to the World Health Organisation (WHO), in 2012, 745,000 deaths were registered worldwide due to this cause, a figure only surpassed by lung cancer. The most aggressive and frequent form of liver cancer is hepato-cellular carcinoma (HCC); […]
High-fat diet postpones brain aging in mice
New Danish-led research suggests that signs of brain aging can be postponed in mice if placed on a high-fat diet. In the long term, this opens the possibility of treatment of children suffering from premature aging and patients with Alzheimer’s and Parkinson’s disease. The research project is headed by the Center for Healthy Aging, University […]
Lead linked to obesity in mice exposed by mothers
When we think of ill effects from lead exposure various neurologic problems usually come to mind. Now researchers at the University of Michigan say another health impact can be added to the list: obesity. Even at low levels, lead is associated with obesity in mice whose mothers were exposed to the chemical, researchers at the […]
Omega 3 fatty acids lessen severity of osteoarthritis in mice
Mice consuming a supplement of omega 3 fatty acids had healthier joints than those fed diets high in saturated fats and omega 6 fatty acids, according to Duke Medicine researchers. The findings, published in the Annals of the Rheumatic Diseases, suggest that unhealthy dietary fats – not just obesity – may contribute to worsening osteoarthritis. […]
Blocking pain receptors extends lifespan, boosts metabolism in mice
Blocking a pain receptor in mice not only extends their lifespan, it also gives them a more youthful metabolism, including an improved insulin response that allows them to deal better with high blood sugar. “We think that blocking this pain receptor and pathway could be very, very useful not only for relieving pain, but for […]
Gluten-free diet reduces risk of type 1 diabetes in mice
New experiments on mice show, that mouse mothers can protect their pups from developing type 1 diabetes by eating a gluten-free diet. According to preliminary studies by reseachers at the University of Copenhagen, the findings may apply to humans. More than 1% of the Danish population has type 1 diabetes, one of the highest incidence […]
Exercise, surgically removing belly fat improves cognition in obese, diabetic mice
Cognitive decline that often accompanies obesity and diabetes can be reversed with regular exercise or surgical removal of belly fat, scientists report. A drug already used to treat rheumatoid arthritis also helps obese/diabetic adult mice regain their ability to learn and comprehend, while transplanting belly fat to a normal mouse reduces those abilities, said Dr. […]