diabetes
Cell signaling pathway linked to obesity, type 2 diabetes
A Purdue University study shows that Notch signaling, a key biological pathway tied to development and cell communication, also plays an important role in the onset of obesity and Type 2 diabetes, a discovery that offers new targets for treatment. A research team led by Shihuan Kuang, associate professor of animal sciences, found that blocking […]
Pesticide DDT linked to slow metabolism, obesity and diabetes, mouse study finds
Exposure of pregnant mice to the pesticide DDT is linked to an increased risk of obesity, diabetes, high cholesterol and related conditions in female offspring later in life, according to a study led by the University of California, Davis. The study, published online July 30 in the journal PLOS ONE, is the first to show […]
New brain pathways for understanding type 2 diabetes and obesity uncovered
Researchers at UT Southwestern Medical Center have identified neural pathways that increase understanding of how the brain regulates body weight, energy expenditure, and blood glucose levels — a discovery that can lead to new therapies for treating Type 2 diabetes and obesity. The study, published in Nature Neuroscience, found that melanocortin 4 receptors (MC4Rs) expressed […]
Why weight-loss surgery cures diabetes: New clues
Scientists at The University of Manchester are a step closer to understanding why diabetes is cured in the majority of patients that undergo gastric bypass surgery. The research, published in the journal Endocrinology, shows the cure is likely to be explained by the actions of specialized cells in the intestine that secrete a cocktail of […]
Insulin pumps result in better blood sugar control than multiple daily injections in people with type 2 diabetes
Type 2 diabetes is usually controlled by diet and medication, but most people with advanced disease also end up needing insulin therapy to achieve control of their blood sugar. However, roughly a third of these patients struggle to achieve the right level of blood sugar control with insulin injections many times a day. The growing […]
Vitamin A derivative potentially treats type 2 diabetes, prevents its cardiovascular complications
At a time when obesity, type 2 diabetes, and their complications are a veritable epidemic worldwide, researchers at the University of Montreal and CHUM Research Centre (CRCHUM) recently demonstrated the potential of retinoic acid (RA), a derivative of Vitamin A, in treating obesity and type 2 diabetes and preventing their cardiovascular complications. The findings were […]
Genetic code for diabetes in Greenland broken by scientists
A spectacular piece of detective work has mapped a special gene variant among Greenlanders which plays a particularly important role in the development of type 2 diabetes. The results have been published in Nature and can be used to improve prevention and treatment options for those genetically at-risk. In collaboration with Greenland researchers from Steno […]
Canola oil may be an oil of choice for people with type 2 diabetes
Canola* is Canada’s oil and new research from St. Michael’s Hospital suggests it should also be one of the oils of choice for people with Type 2 diabetes. Dr. David Jenkins, head of the hospital’s Clinical Nutrition and Risk Factor Modification Centre, compared people with Type 2 diabetes who ate either a low glycemic index […]
Activating immune system could treat obesity, diabetes
Obesity is a worldwide epidemic that is causing alarming rates of diabetes and cardiovascular disease, but currently there is a lack of effective drug treatments. Two unrelated studies published by Cell Press June 5th in the journal Cell reveal an important role for immune pathways in activating good types body fat, called brown and beige […]
More than 10 percent of heart attack patients may have undiagnosed diabetes
At least 10 percent of people who have a heart attack may have undiagnosed diabetes, according to new research presented at the American Heart Association’s Quality of Care and Outcomes Research Scientific Sessions 2014. Researchers studied data on 2,854 heart attack patients who did not have a known diagnosis of diabetes in 24 U.S. hospitals […]