2014/06/e0790_fitness_41blxSj9PCL._SL160_

Genetic code for diabetes in Greenland broken by scientists

A spectacular piece of detective work has mapped a special gene variant among Greenlanders which plays a particularly important role in the development of type 2 diabetes. The results have been published in Nature and can be used to improve prevention and treatment options for those genetically at-risk.

In collaboration with Greenland researchers from Steno Diabetes Center and University of Southern Denmark, researchers from the University of Copenhagen have carried out the ground-breaking genetic analysis based on blood samples from 5,000 people or approximately 10% of the modestly-sized population inhabiting an area larger than western Europe.

“We have found a gene variant in the population of Greenland which markedly increases the risk of developing type 2 diabetes. The gene variant is only found in Greenlanders and explains 15% of cases of diabetes in the country,” explains Professor Torben Hansen from the Novo Nordisk Foundation Center for Basic Metabolic Researchat the University of Copenhagen who conducts research into the link between our genetic make-up and the development of diabetes and obesity as well as the effect of treatment. Together with Associate Professor Anders Albrechtsen from the Bioinformatics Centreat the University of Copenhagen, he is the driving force behind the findings.

The study was a challenge in several ways. Collecting samples from 10% of the population of such a big country was a huge logistical task, and it was only possible because so many Greenlanders volunteered to participate. Additionally, the study was a statistical challenge as many of the participants are of both Inuit and European ancestry — and because many of the participants are related:

“For some of the analyses, we therefore had to develop new methods, and for others, we used methods which were only developed recently,” explains postdoc Ida Moltke from the Department of Human Genetics at the University of Chicago. She is one of the two first authors of the article and responsible for the statistical analyses.

Potent gene variant

By means of advanced gene chip technology — which over the past ten years has led to a marked increase in the speed of genetic analyses — the Danish team analysed the 5,000 blood samples for 250,000 gene variants which play a role in metabolic diseases such as diabetes, obesity and cardiovascular disease.

“Our attention was quite soon caught by a particular variant of the TBC1D4 gene which controls glucose uptake in muscle cells. Roughly speaking, this means that in carriers of this particular gene variant, the uptake of glucose by the muscles is hampered, for example after a meal which results in raised blood glucose levels. However, this particular gene variant is primarily found in Greenlanders, and about 23% of the Greenlandic population are carriers of the variant which prevents the optimum functioning of the glucose transporters in the cells. The gene variant is not found in Europeans at all,” explains Assistant Professor Niels Grarup from the Novo Nordisk Foundation Center

… Continue reading here.
Diet And Weight Loss News — Sciencedaily
— Courtesy “Science News Daily” (ScienceNewsDaily.com) <p>

OPEN ME!! This video is all about my diet and fitness routine. It was very highly requested so i decided to make it. Remember, i am not a professional nutrit…

<p>[wpramazon asin=”B0006U843O”]


You May Also Like These Topics...
2 women playing soccer on green grass field during daytime

You Can Help Your Child Get More Exercise By Following These 5 Tips

Does your child get enough exercise? You can get your children more active with these 5 fun parenting tips.

man in black t-shirt and black shorts running on road during daytime

Better Health in Four Steps

In just four steps, you can improve your health for the better and this article will show you how. The steps below are bite-sized nuggets of health information you can actually use to live a healthy life. Here we go… Nutritional supplements are the first step As far as I’m concerned, they are very important […]

Top 4 Nutrition Predictions in the New Year

Several food and nutrition trends were in the spotlight this year, including the continued rise of plant-based diets, non-dairy ice creams and superfoods that are blasts from the past — legumes, apples and cabbage. It can be easy to experience nutrition whiplash in the New Year, but don’t be a victim. Get a jump-start on […]

Want to lose weight? Research proves a big breakfast is the first step

If you want to lose weight, you’re not alone. More than half of Americans desire to shed pounds, according to Gallup. This goal inspires people to take action in many ways, from increasing exercise to modifying meals. One thing many people do is skip breakfast in order to lower calorie intake. While this may seem […]

Tags: , , , , , ,
Previous Post
2014/06/3b8d4_exercise_41uunOH45oL._SL160_
Healthy Lifestyle

Vitamin A derivative potentially treats type 2 diabetes, prevents its cardiovascular complications

Next Post
s42191
Healthy Lifestyle Strength Training Walking & Hikiing Yoga

Yoga exercise program tailored for pulmonary hypertension patients

Comments

    • tish
    • June 19, 2014
    Reply

    can you please do an updated diet and fitness video? i found this one
    really helpful
    thanks xxx

    • Kirstin Krader
    • June 19, 2014
    Reply

    Do yoga! its fun :)

    • Kathryn Navkav
    • June 19, 2014
    Reply

    I wish I was like this! Since middle school I’ve been worried about my
    weight! I workout usually five to six times a week and watch what I eat so
    that I don’t gain weight! Oh well, and yes I love yoga and Pilates please
    take both your flexibility will greatly increase and you’ll feel great!

    • Ashley Han
    • June 19, 2014
    Reply

    u look like emma stone in this video :D

    • Kiko Navala
    • June 19, 2014
    Reply

    I am skinny and small too! Hopefully i will become pretty as you when im
    older. By the way im a tween/pre teen. :)

    • Safak Nalcakan
    • June 19, 2014
    Reply

    how tall are you?

    • Ally Spak
    • June 19, 2014
    Reply

    can you do a hair tutorial for this hair style? 🙂 its GORGG 

    • Evie Crawford
    • June 19, 2014
    Reply

    “I hate the tread mill, i absolutely hate the treadmill like i really hate
    the treadmill, hate it”

    • Abby Mitchell
    • June 19, 2014
    Reply

    Can you do a video on your different curled hair styles because you almost
    always seem to have a different type of curl and it is always GORGOUS! 

    • theWolverine
    • June 19, 2014
    Reply

    God graced with Beauty! Gorgeous!

    • selinabella09
    • June 19, 2014
    Reply

    Great video!

    • Summer Sunshine
    • June 19, 2014
    Reply

    Ur hair looks cute!

    • Sassy Alexandria
    • June 19, 2014
    Reply

    I love yoga!!! I don’t take classes because of my busy schedule, but I
    bought a yoga disc and I do it at home. Ps- can you do a tanning video? I
    really need one but I don’t know what to use

    • Maya Farrell
    • June 19, 2014
    Reply

    God your gorgeous

    • rachel garritano
    • June 19, 2014
    Reply

    Zumba is great!! I love it! I go 2 times a week 🙂

    • Buyer
    • June 19, 2014
    Reply
    168 of 176 people found the following review helpful
    5.0 out of 5 stars
    Great Product for a Great Price!!!, August 10, 2005
    By 
    Buyer

    This review is from: Max Fitness 65cm Exercise Ball with Foot Pump (Pearl White) (Sports)
    I train people for a living and have sent all of my clients to this seller for their exercise balls. Being one that works with different sized people on a daily basis on the Max Fitness balls, I can tell you that they provide a great product and they are very fast to get it to my clients. I own one myself. Thanks for the great product and service.

    Jason P

    0

    Help other customers find the most helpful reviews 

    Was this review helpful to you? Yes
    No

    • Shanni
    • June 19, 2014
    Reply
    86 of 92 people found the following review helpful
    5.0 out of 5 stars
    I love my exercise ball!, January 19, 2007
    By 
    Shanni (Los Angeles, CA) –

    Verified Purchase(What’s this?)
    This review is from: Max Fitness 65cm Exercise Ball with Foot Pump (Pearl White) (Sports)
    I ordered this ball because I didn’t like the bright colors at my local stores. I wanted something neutral that wouldn’t stick out like a sore thumb in my home. The shipping from Max Ltd. was super fast and the ball was pretty quick and easy to inflate.

    I actually bought this as a “birth ball”. I’m 8 months pregnant and sitting on the ball helps relieve back pain/pressure, hip rocks feel great on it. Gently bouncing on it has gotten my baby down into position! I’ll be using the ball during labor and after I have my baby. Babies love to be bounced on it and it’s a comfortable seat to nurse on. I’ll also be using it a few months after the birth to work out on and drop my pregnancy weight.

    0

    Help other customers find the most helpful reviews 

    Was this review helpful to you? Yes
    No

    • LolaV
    • June 19, 2014
    Reply
    43 of 48 people found the following review helpful
    5.0 out of 5 stars
    just like the ones you use at the gym.., May 14, 2007
    By 
    LolaV (Washington DC) –

    Verified Purchase(What’s this?)
    This review is from: Max Fitness 65cm Exercise Ball with Foot Pump (Pearl White) (Sports)
    I first started using excercising balls at the gym, and loved it. I went and bought one.. and for some reason, it just wasn’t the same. A girlfriend of mine also got me one, and again.. just not what I was used to.. then I ordered this one, and it was exactly like the one I used at the gym.. and cheaper than the other ones I had. SO, I highly recommend this. Read the directions and do do another round of air the next day.. its perfect.

    0

    Help other customers find the most helpful reviews 

    Was this review helpful to you? Yes
    No

Leave a Reply

0 Shares
Tweet
Share
Share
Pin