Parkinson’s disease (PD), a neurodegenerative disease of the substantia nigra, was first discovered and its symptoms documented in 1817. This discovery and docomentation was by British physician Dr. James Parkinson. It wasn’t until the 1960’s that the associated biochemical changes in the brain of patients were able to be identified. Although many genes have recently been identified, there are still several others that remain unkown. Parkinson’s disease involves a progressive movement disorder of the extrapyramidal system. The extrapyramidal system controls and adjusts communication between neurons in the brain and muscles in the human body. As you can see this is a huge, and important task. PD will commonly coincide with depression and disturbances of sensory systems due to the damage that it has on the brain. Aprroximately one out of every 600 people have Parkinson’s disease in the United States of America. The rates increase with age, especially apparent in those over 55.
Still unknown, is the cause of Parkinson’s disease. 9 different genetic defects have been found. Each of these nine cause the disease in 1 or a few more familes with extremely high incidences of the disease. This unfortunately hasn’t take geneticists further as these familes are so rare to find. Although strong inheritance patterns are extremely rare, an person who is infected with PD is 3 to 4 times more likely to have a close relative who also has PD.
Today the strongest theory for the cause of Parkinson’s disease is from “the combination of a subtle genetically-determined vulnerability to environmental toxins along with even limited exposure to those toxins. The toxins most strongly suspected at present are certain pesticides and industrial metals.”
I wish that I had an answer like many others do to the cause of Parkinson’s. One thing that we know though, is that as science and technology increases, so will man’s understanding of diseases such as Parkinson’s.
Related articles from around the web:
Related searches: Parkinsons Disease, United States, Parkinson’s disease, Barack Obama, Cold War, Cuba, Neuron, AFFiRiS, Alzheimer’s disease, Beta amyloid, Christmas,
The image shows dopaminergic pathways of the human brain in normal condition (left) and Parkinsons Disease (right). Red Arrows indicate suppression of the target, blue arrows indicate stimulation of target structure. (Photo credit: Wikipedia)
English: Drawing of the face of a Parkinson’s disease patient showing characteristic symptoms: mainly hypomimia, a expression-less mask-like face. Appeared in Nouvelle iconographie de la Salp ©tri re 1 : clinique des maladies du syst me nerveux / publi ©e sous la direction du professeur Charcot,… ; par Paul Richer,… Gilles de la Tourette,… Albert Londe,…. – 1888. Chapter “Habitude exterieure et facies dans la paralyse agitante”. Plate XL1V (Photo credit: Wikipedia)
Start living a healthy life now: Here is your 7-day plan ==> Having sworn to yourself that you’ll go to the gym in the morning, how many times have you changed your mind after you woke up and did not feel like working out? We all have days when we lose our motivation to get […]
A recent study shows your perception of your own image has a profound effect on how you present yourself to the rest of the world. Those findings could be empowering since even small changes to your self-care routine can significantly boost your self-confidence. The study by researchers at the Stanford Graduate School of Business found […]
(BPT) – Setting intentions is a powerful thing. Then when you have that shiny new gym membership in hand, you feel like nothing stands between you and your goals to get in shape once and for all. Trouble is, lack of motivation, unpreparedness and busy schedules have a way of interfering with our plans. If […]
(BPT) – Being an informed health care consumer is hard work. There is information everywhere. But how do you sift through it and make sense of it all? And how do you know what is reliable and what isn’t? Sorting through the noise when buying hearing aids is no exception. In the past several months, […]