Healthy Aging: Its In Your Genes But New Research Study Suggests You Can Take Steps To Shift The Balance.

This article is sponsored by Health, Fitness & Body Building

Wyckoff, NJ (PRWEB) August 29, 2013

A new research study conducted by Serena Dato et al.*, and published in the August 2013 issue of the International Journal of Molecular Sciences, cites oxidative stress as both the cause and consequence of impaired functional homeostasis characterizing human aging. The diminishing efficiency of our natural response to oxidative stress as we age represents a health risk and leads to the onset and progression of major age-related diseases.

The authors believe that in contrast to normal aging, centenarians seem to have evolved conservative stress response mechanisms, probably derived from a combination of a diet rich in natural antioxidants, an active lifestyle and a favorable genetic background. A favorable genetic make-up accounts for about 25% of the variation in human lifespan and is characterized as being particularly rich in genetic variants that are able to counteract the stress overload at the level of both nuclear and mitochondrial DNA.

The response to oxidative stress is a highly complex system that involves an integrated network of molecular activities, ranging from immunity to inflammatory activation and regulation, to glucose homeostasis and mitochondrial metabolism. Human longevity is believed to be associated with maintaining the complexity in the physiological pathways for dealing with stressors within the cell.

The study authors state that centenarians are believed to be endowed with a genetically favorable stress control system, but even if not so endowed, steps can be taken to maintain the control system required to support healthy aging. The lifestyle factors that have the greatest impact on our oxidative stress response include impaired nutrition, reduced physical activity, alcohol consumption, and cigarette smoking. Physical activity and diet, in particular, have been suggested to seriously influence the oxidative stress response in humans, tipping the balance of oxidative burden/antioxidant response to one side or the other.

A common marker of aging is the progressive decline in physical activity levels, but regular physical activity is able to improve metabolic status and insulin sensitivity, as well as modulate age-related changes in weight and body composition in older individuals. Overall, a well-balanced and healthy eating plan, with fewer calorie dishes, rich in vegetables and fruits but low in animal fats, red meat and carbohydrates, can allow the long-lived to benefit from antioxidant natural defenses and also to maintain a healthy weight.

Editor’s note: If you are on a budget, check out these Tips to Eating Healthy on a Budget

The authors conclude that genetic background undeniably has an important role in the individuals ability to counteract oxidative stress and to delay the effects of aging, but much can be done to minimize the stress load we typically endure. In particular, a simple strategy for healthy aging for the elderly population should be to adopt a moderate physically active lifestyle and to ensure an adequate intake of dietary antioxidants to minimize oxidative stress to a basic level.

The conclusions reached by the authors of the study on Healthy Aging & Human Longevity represent the best thinking of investigators who work in this area, stated Gerald Bruno, Ph.D., Founder of Ethical Alternative Products. While few would argue with these conclusions, only a small number of people within our aging population will effectively and consistently incorporate these lifestyle changes into their everyday life stated Bruno. Unfortunately, many seniors are precluded from even moderate physical activity because of joint pain, and few can consistently maintain a diet that is rich in natural antioxidants. The OmniFlex joint health supplement was developed to facilitate restoration of joint mobility, and ThioGel solubilized alpha lipoic acid is a high bioavailable formulation that supplements lifestyle changes aimed a counteracting oxidative stress stated Bruno.

A complementary trial bottle of OmniFlex can be obtained at http://www.getomniflex.com[1] and a trial bottle of ThioGel can be obtained at http://www.thiogel.com[2].

About Ethical Alternative Products Ethical Alternative Products is a dietary supplement supplier that is focused on the research and manufacturing of a select group of scientifically sound, broad-use supplement products. The company mission is to develop and produce high-value supplements, employing innovative formulations and the highest quality raw materials. Products produced by Ethical Alternative Products include ThioGel, ThioGel-L triple antioxidant liver formulation, OmniFlex multi-nutrient joint health product and Tendonex topical pain reliever.

*Exploring the Role of Genetic Variability and Lifestyle in Oxidative Stress Response for Healthy Aging and Longevity. Serena Dato, Paolina Crocco, Patrizia DAquila, Francesco de Rango, Dina Bellizzi, Giuseppina Rose and Giuseppe Passarino Int. J. Mol. Sci. 2013, 14, 16443-16472; doi:10.3390/ijms140816443 http://www.mdpi.com/1422-0067/14/8/16443[3]


  1. ^ http://www.getomniflex.com (www.getomniflex.com)
  2. ^ http://www.thiogel.com (www.thiogel.com)
  3. ^ http://www.mdpi.com/1422-0067/14/8/16443 (www.mdpi.com)

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  1. Reply

    How The Computer Is Supporting Us In Our Healthy Lifestyle? How do computer helps people in their healthy lifestyle? How can The computer help people? Is it from websites? advertisements? I need it really badly. How can the computer is supporting to improve our healthy lifestyle. in what ways? How can computer promote the quality of healthy lifestyle. How can computer convince people to stop unnecessary things like drugs or alcohol? How can computer HELP us?
    AT least 6-8 points would do. thank you.

      • HealthNut
      • September 1, 2013

      The computer is not a healthy lifestyle for people. It programs us to thinking we can find everything on here. Jobs, pay bills, shop, everything! We can do that ourselves and it seems technology is taking the chores away from us, that can be easily done by human themself. The computer can help us though when we need to find information, imformation fast. Websites help us retain information, advertisements are just like commericals there just trying to sell or maniupulate us to buy whatever their advertising. The computer is not improving our healthy lifestyle. Peoples eyes can go out of sight and hurt very badly(like mine and i’m only 15 years old.) from years and years staring at the computer. The worst thing to stare at is a computer screen — I don’t know why I still do it for hours at end, but I do. The computer will never promote the quality of healthy lifestyle, its just not possible. The computer can convince people to stop drugs and alcohol but if you think about it would you rather have an obsession over the computer for hours at the day, you have to be near the computer you have to be on it then doing drugs or alcohol? The computer is just as bad addiction as alcohol and drugs. The computer cannot HELP us other then give us fast information when we need it. The computer although has so much information and so many untrusted sites you never know if what your reading is a lie. And I hope I get 10 points because I just wasted my time answering this long question, I hope you weren’t just asking this for the heck of this — I hope it was for some essay lol.

      Take care bye

  2. Reply

    How Can I Keep Up My Healthy Lifestyle Over Easter? I have been trying to keep a healthy lifestyle, build fitness and lose a little fat. But I am surrounded by Easter treats, mum has been baking loads, have Easter eggs from family and my bf wants to get me an Easter egg too. Don’t get me wrong, I love how sweet everyone is being, but all of this will just make me I’ll. What should I do?

      • HealthNut
      • September 1, 2013

      If you’d like me to be honest, I think that the healthiest lifestyles include enjoying things. So every now and then, let go of the fact that “something will make me fat” and enjoy it. I think that often as people we give up a large part of living just to stay skinny. I used to be that way, and as much as I told myself it was worth it, it really wasn’t. Enjoy it, and don’t go on a guilt trip over it.

      That being said, there are several things you can do to avoid extra treats. Stay away from the kitchen as much as possible, as well as where things are being served. When you get things, get just a small bit. I’ve noticed that with a lot of sweetbreads and cakes and such, a very thin slice takes just as long to eat as a thick one and is usually just as satisfying. If not, you can even get a second (which, sliced thinly enough, is still smaller than the thick slices would be). Another trick I’ve learned is “sharing”–if it is a roll or whatever, just eat half of it and “share” the other half with someone else (maybe someone else who either just wants half, or someone who wants more than one).

      Enjoy Easter!

  3. Reply

    How Will You Maintain A Healthy Lifestyle In The Future? Imagine yourself after college. You’re married with a few kids. You’re gaining a few pounds every now and then. How will you get yourself back on track into a healthy lifestyle?

      • HealthNut
      • September 1, 2013

      Minus the after college part, but I have 2 kids and am expecting the third one in a few weeks. We maintain healthy lifestyles by eating nutritious foods, lots of whole grains, fruits, veggies, and milk. We also get a lot of exercise in. Although my kids are still toddlers and I’m big as a house, everyday as a family my husband and I walk with the kids up and down the road, then when we get home my husband stays outside with the kids and plays with them while I get supper fixed. We don’t turn the TV on until after baths, forcing us to get up off the couch. Hopefully that will encourage our kids to maintain healthy lifestyles after they’re all grown up.

  4. Reply

    What Can Anyone Do To Promote A Healthy Lifestyle? What can institutions such as schools do and what can individuals do?
    What can the government put in place?
    What is the reason for the fact not a lot of people care about having a healthy lifestyle anymore?

      • HealthNut
      • September 1, 2013

      Schools can replace all or most of the canteen food with healthy options so they could replace chicken burger with tuna salad for example. Individuals can aim to eat 5 portions of fruit and veg a day and exercise for at least 30 minutes a day. The government can put a higher price up on junk food, therefore tempting more people to buy healthy food as it would become cheaper than it is now.

      The reason why people don’t care about a healthy lifestyle, is that junk food like burger and chips is quick and a convenience, as healthy meals takes time to prepare. Same with exercise maybe being time consuming and they have a busy schedule to be able to fit it all in.

    • Alice
    • September 1, 2013

    How Do You Maintain A Healthy Lifestyle? Please comment on your suggestions to maintain a healthy lifestyle, add any concerns or issues you have concerning you’re healt, and i’ll be happy to educate you further.

      • HealthNut
      • September 1, 2013

      I eat healthy – vegetables, fruit, lots of water, minimal sugar consumption, etc.
      I don’t smoke.
      I don’t drink in excess.
      I don’t do drugs.
      I exercise at least twice a week.
      I try to get enough sleep every night (minimum of 7 hours).

  5. Reply

    What Would You Say A Healthy Lifestyle Is? Hey 🙂 I’ve got some coursework that needs doing and I need to do some primary reasearch and I was just wondering if you would leave me some answers below on what you think a healthy lifestyle is personally. And what you think you have to do to maintain a healthy lifestyle. I need loads of answers so I hope you dont mind helping me 🙂 Thankyouu

      • HealthNut
      • September 1, 2013

      Healthy lifestyle…involves eating right, exercing, and relationships you have with others. Also if you live in a clean environment…messy=germs=sickness…and to maintain a healthy lifestyle you need to frequenlty eat right, do some sort of physical activity, be nice to others (stress is bad for health), and keep a clean home

  6. Reply

    How To Keep A Healthy Lifestyle Up At School? I’ve recently started exercising and eating healthily, in order to achieve a healthy lifestyle, as well as lose weight. I go back to school in September, and I’ve been doing absolutely brilliantly so far. However, I’m definitely a stress eater, and especially with lots of exams coming up this and next year, I’m gonna be more stressed than ever. I don’t want to lose my progress or put all the weight back on. As well as this, I’m worried I won’t have time to work out as I’ll be tired from school in the daytime, so it could get difficult. Does anyone have any tips that could help me maintain what I’m doing for when I go back to school?

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