Taking folic acid before conception significantly reduces the risk of small for gestational age (SGA) at birth, suggests a new study published today (26 November) in BJOG: An International Journal of Obstetrics and Gynaecology (BJOG).
This UK population-based study and systematic review assessed the effect of timing of folic acid supplementation during pregnancy on the risk of the baby being SGA at birth, defined as birth weight less than the 10th centile or in the lowest 10% of babies born.
Being small for gestational age is associated with increased neonatal morbidity and mortality and an increased risk of chronic diseases in later life such as diabetes, hypertension, obesity, cardiovascular disease and mental health problems, states the study.
Folic acid supplementation has already been shown to reduce the risk of neural tube defects, such as spina bifida, and it is recommended in the UK for women to start folic acid supplementation pre-conceptually. However, uptake is low, state the authors, and previous studies have suggested rates of pre-conceptual uptake to be between 14.8% and 31%, with lower uptake in younger age groups and ethnic minorities.
The total study population represents a diverse group, with a mean maternal age of 28.7 years, a median BMI of 24.7 and 42% were first time mothers. Additionally, the majority were non-smokers (81.7%).
Of 108,525 pregnancies with information about folic acid supplementation, 84.9% had taken folic acid during pregnancy. Time of commencement of supplementation was recorded in 39,416 pregnancies, of which folic acid was commenced before conception in 25.5% of cases.
Results show that the overall proportion of babies with a birth weight under the 10th and 5th centile was 13.4% and 7% respectively. The highest rate of SGA occurred in pregnancies where no folate had been taken, with 16.3% under the 10th centile and 8.9% under the 5th centile.
When comparing pre- and post-conceptual folic acid supplementation, the prevalence of birth weight lower than the 10th centile was 9.9% and 13.8% respectively, while that of birth weight under the 5th centile was 4.8% and 7.1% respectively.
The authors conclude that although folic acid supplementation is a standard recommendation in the UK, it is a policy that is poorly followed and strategies to increase uptake must be evaluated.
Additionally, further research is needed to focus on how folic acid supplementation produces its effect on birth weight and how the dose of supplementation can be optimised in women considered to be at higher risk of SGA, state the authors.
Khaled Ismail, Professor of Obstetrics and Gynaecology at the University of Birmingham and co-author of the study said:
“Increased uptake of folic acid prior to pregnancy and throughout the first trimester could have significant public health benefits given the poor outcomes associated with SGA babies. New strategies are therefore vital to improve the lives of both mothers and babies.”
John Thorp, BJOG Deputy Editor-in-chief, added: “The population study is the largest database to look at
… Continue reading here.
Diet And Weight Loss News — Sciencedaily
— Courtesy “Science News Daily” (ScienceNewsDaily.com)
A few of my diet and fitness tips that I use to stay in shape and healthy!!! For the cute capri leggings I mentioned use the coupon code “STYLIST20” to get 2…
You, a Few Friends and a Lunchtime Workout!
Limit 1 voucher Limit 3 vouchers as gifts Offer expires 6 months from date of purchase No cash back, no credit given Not to be combined with any other offers or discounts Appointments are required and subject to availability Merchant cancellation/re-scheduling policy of 24 hours applies; voucher subject to forfeiture Each voucher must be redeemed by a different individual Available for use beginning the day after purchase
Price: $ 50.00
Sold by [wpramazon asin=”B001U0OFDC”]
You Can Help Your Child Get More Exercise By Following These 5 Tips
Does your child get enough exercise? You can get your children more active with these 5 fun parenting tips.
Better Health in Four Steps
In just four steps, you can improve your health for the better and this article will show you how. The steps below are bite-sized nuggets of health information you can actually use to live a healthy life. Here we go… Nutritional supplements are the first step As far as I’m concerned, they are very important […]
Top 4 Nutrition Predictions in the New Year
Several food and nutrition trends were in the spotlight this year, including the continued rise of plant-based diets, non-dairy ice creams and superfoods that are blasts from the past — legumes, apples and cabbage. It can be easy to experience nutrition whiplash in the New Year, but don’t be a victim. Get a jump-start on […]
Want to lose weight? Research proves a big breakfast is the first step
If you want to lose weight, you’re not alone. More than half of Americans desire to shed pounds, according to Gallup. This goal inspires people to take action in many ways, from increasing exercise to modifying meals. One thing many people do is skip breakfast in order to lower calorie intake. While this may seem […]