Heat regulation dysfunction may stop MS patients from exercising

Exercise can be beneficial for patients with multiple sclerosis, a degenerative nerve disease that progressively impairs central nervous system function. However, for some patients, a rise in body temperature, which occurs during exercise and/or exposure to hot and humid conditions, can make symptoms temporarily worse. Researchers at Southern Methodist University collaborating with colleagues from University of Sydney set out to explore how moderate exercise affected patients with MS compared with healthy control subjects. Mu Huang, will present the research team’s findings in a poster session on Tuesday, April 29, at the Experimental Biology meeting.

Experimental Biology is an annual meeting comprised of more than 14,000 scientists and exhibitors from six sponsoring societies and multiple guest societies. With a mission to share the newest scientific concepts and research findings shaping current and future clinical advances, the meeting offers an unparalleled opportunity for exchange among scientists from throughout across the United States and the world who represent dozens of scientific areas, from laboratory to translational to clinical research. www.experimentalbiology.org

Huang et al. asked five patients with MS and five control subjects to cycle in a temperature-controlled room for 30-60 minutes. They found that sweating took longer to start and sweat rate was lower during exercise-induced body temperature increases in MS patients compared to healthy control subjects. This altered temperature regulation also led to a greater increase in core temperature among the MS patients vs. controls. Overheating in this way could cause a temporary worsening of symptoms, which may impact the ability to exercise or discourage patients with MS from exercising.

“While preliminary, these findings suggest that a larger rise in body temperature seen in MS patients is due to a lower sweat rate and a delay in the start of sweating thereby limiting the body’s ability to cool itself down. A greater understanding of how MS affects the body’s ability to dissipate heat during exercise will provide insight into ways of reducing the impact of heat intolerance and improving the safety and benefit of exercise for MS patients,” researchers noted.

Story Source:

The above story is based on materials provided by Federation of American Societies for Experimental Biology (FASEB). Note: Materials may be edited for content and length.

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Federation of American Societies for Experimental Biology (FASEB). “Heat regulation dysfunction may stop MS patients from exercising.” ScienceDaily. ScienceDaily, 29 April 2014. <www.sciencedaily.

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Fitness News — Sciencedaily
— Courtesy “Science News Daily” (ScienceNewsDaily.com) <p> <p>Question by Ferret Face: Why should people with arthritis exercise?
I’ve always heard that people with arthritis should exercise, but other then it’s generally good to exercise…

Since arthritis is painful, wouldn’t exercise just make it more painful and cause more damage?

Best answer:

Answer by ★☆W.a.b.b.y✿❀
Exercise when you have arthritis is one of the best things you can do!

Exercising while you have arthritis should not hurt. If it hurts, then you should stop. But exercising can help to build the muscle around the joint, thus strengthening it and causing less pain.

If you have inflammatory/autoimmune arthritis (i.e. Rheumatoid, Lupus, Psoriatic) then you should not exercise when you have swollen joints.


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    • Loma
    • April 30, 2014

    Exercise is the best medicine for you if you have arthritis. Believe it when you are told that it’s best when you move, a body at rest will stay at rest and a body in motion will stay in motion. Movement helps the muscles by strengthen them so you have less pain. Physical Therapy is a good option to help strengthen your muscle and provides better mobility. You will learn the right exercise to do for your specific areas of pain. There are some medical supplements that many people find helpful such as Congrotine and Gllucosamine. And if you are over weight, it’s best to lose a few pounds because it will lessen the pressure on your joints. I have an article on Arthritic Knees in my blog if you want more information on this topic at http://caregiversclinic.com

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