Maternal supplementation with multiple micronutrients compared with iron-folic acid

Maternal supplementation with multiple micronutrients compared with iron-folic acid

In Bangladesh, daily maternal supplementation of multiple micronutrients compared to iron-folic acid before and after childbirth did not reduce all-cause infant mortality to age 6 months, but did result in significant reductions in preterm birth and low birth weight, according to a study in the December 24/31 issue of JAMA.

Multiple micronutrient deficiencies are common among pregnant women in resource-poor regions of the world, especially in southern Asia. Coexisting with poor maternal nutrition across the region are excessive burdens of low birth weight (LBW), preterm birth, small size for gestational age, stillbirth, infant mortality, and maternal mortality. Gestational micronutrient deficiencies may contribute to avertable adverse birth outcomes. Data for effects of antenatal (before birth) multiple micronutrient (MM) supplementation on longer-term infant mortality are sparse for guiding policies in southern Asia, according to background information in the article.

Keith P. West Jr., Dr.P.H., of the Johns Hopkins Bloomberg School of Public Health, Baltimore, and colleagues conducted a study in which pregnant women in Bangladesh (n = 44,567) were randomly assigned to receive supplements containing 15 micronutrients or iron-folic acid alone, taken daily from early pregnancy to 12 weeks postpartum.

Among the 22,405 pregnancies in the multiple micronutrient group and the 22,162 pregnancies in the iron-folic acid group, there were 14,374 and 14,142 live-born infants, respectively, included in the analysis. At 6 months, multiple micronutrients did not significantly reduce infant mortality; there were 764 deaths (54.0 per 1,000 live births) in the iron-folic acid group and 741 deaths (51.6 per 1,000 live births) in the multiple micronutrient group.

Multiple micronutrient supplementation resulted in a non-statistically significant reduction in stillbirths (43.1 vs 48.2 per 1,000 births) and significant reductions in preterm births (18.6 vs 21.8 per 100 live births) and low birth weight (40.2 vs 45.7 per 100 live births).


“Our study’s null finding is in agreement with a small number of trials that have provided an antenatal multiple micronutrient vs iron supplement, with or without folic acid, and found no effect on neonatal mortality,” the authors write.

“Reasons for a null effect on postnatal survival after improvement in some birth outcomes with antenatal multiple micronutrient supplement use remain unknown but may reflect a complex interplay between maternal and newborn sizes and differential responses to supplementation by causes of death.”

Story Source:

The above story is based on materials provided by JAMA – Journal of the American Medical Association. Note: Materials may be edited for content and length.

Original story here.
Diet And Weight Loss News — Sciencedaily
— Courtesy “Science News Daily” (

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24 Responses to “Maternal supplementation with multiple micronutrients compared with iron-folic acid”

  1. Tony Horton Reply

    NEVER-BEFORE-SEEN FOOTAGE walking you through my HOME GYM in Santa Monica,
    CA! #TonyHorton

    View Comment
  2. junaidfromthebronx Reply

    Hi Tony. Can you make a video of you doing muscle ups? I’m curious how many
    you could do.

    View Comment
  3. Andrea Baker Reply

    You should make a work out routine with your wife, to show special work
    outs for women, cause I would assume there is different work outs for
    women? If not idk

    View Comment
  4. Holy Hypertrophy Reply

    I love your setup Tony! And all your videos! God bless you and your

    View Comment
  5. Max Schuldes Reply

    Tony, Whats goin on my brotha how are you doing. My name is Maximus (my
    parents are awesome i know). Im 19 years old in college and im gettin in
    pretty good shape 270 down to 243. My buddy let me borrow p90x and its alot
    of fun. Now im getting pretty athletic however the weight situation is at a
    bit of a halt. Do you think maybe you can make a video like this of your
    kitchen? Show us what you got on hand maybe change my kitchen up a bit.
    Ps. My goal is to be a 5k runnin moutain climbing beast by summer and i
    think its on track if i change my diet.
    Thanks alot tony love ya man

    View Comment
  6. makemoneyrelax Reply


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  7. BenG Reply

    Thank you for everything Tony. Can’t begin to explain how much you’ve
    helped me.

    View Comment
  8. papijelly Reply

    Thank you very much Tony ive wonder about all these things ever since I did
    the one on one series, first time I saw your gym then. An sorry about your

    View Comment
  9. R1ProductionHouse Reply

    This is fake guys, the real Tony is 56 years old ;)

    View Comment
  10. Karen B Reply

    All your gym needs is a mook jong, a wooden training dummy, for your
    martial arts training!

    View Comment
  11. Kevin Li Reply

    Beautiful house and setup for all your equipment! Thanks for sharing!

    View Comment
  12. Steven Yager Reply

    Thanks for sharing man. I am slowly adding to my own and this really helps
    alot. Much appreciated.

    View Comment
  13. Blacktolite Reply

    Love the weather there the trees waving so peaceful. I see you gave us
    exclusive on the next px4nice tony px4

    View Comment
  14. Dewey Smith Reply

    Peg board, I man I haven’t played on one in years. I want one.

    View Comment
  15. Alex Phinney Reply

    Can I have Stephanie on my pullup bar? xD lol

    View Comment
  16. pipuk3 Reply

    how has that guy not died yet , losing grip on one of those and cracking
    his head on that concrete.

    View Comment
  17. Screamin Mime Reply

    That’s going to be a lot of gear to send via mail for X4!

    View Comment
  18. FitSoul Reply

    can i live with you, pleaaaseee? *-*

    View Comment
  19. junak777 Reply

    When You are rowing on tradmill do it with just tip of fingers. In rowing
    as You probably know the hand grip is quite different then in baseball for
    example. Tony You have lovely outside and awsome inside gym. I wound not
    change anything except adding swedish ladder(or Arrow’s salmon ladder) with
    some curved plastic gadget as support for spine when soemone lift legs,
    which You probably already have( but I haven’t seen them in video). Great
    work from a great man! Happy holydays!

    View Comment
  20. nickcef Reply

    Tony! That’s definitely a home gym on steroids, buddy! I see you own a few
    of those weight bars. My gym here in the building has a set and I really
    don’t know what the heck to do with those things;) Hint, hint: Maybe you
    could show us a quick routine or two?? And my sincere condolences on the
    passing of your dad. I remember seeing him in Trumbull, CT, when you did
    that camp a couple years back.

    View Comment
  21. ssj3vegett0 Reply

    Great update ! Nice to see The changes after V3 one on one 2010 btw lol,
    Plz plz just answer this for me , I deserve it , I been working out to the
    V 1,2,3 one on ones for 3 years now , it’s your masterpiece to me , much
    more sincere and funny. And I do them all the time. I know there’s THF on
    YouTube , but will there ever be a Volume 4?

    View Comment
  22. Shawn Jimmo Reply

    Tony, you are the real deal! I watched your tour and I see variety and
    functional strength. Thank you for non stop inspiration! Merry Christmas!

    View Comment
  23. Ramon Betances Reply

    First, I would like to say that I admire your work and Im really glad you
    have a youtube page. I’m a big fan. Can you please do a video like this of
    your kitchen? I’m struggling with the nutrition aspect of fitness and I
    would love to see what you stock in your kitchen. This would give me a
    better idea of what to stock in my kitchen.

    Thank you

    View Comment
  24. Luis Fernandez Reply

    That outside is excellent

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