In Bangladesh, daily maternal supplementation of multiple micronutrients compared to iron-folic acid before and after childbirth did not reduce all-cause infant mortality to age 6 months, but did result in significant reductions in preterm birth and low birth weight, according to a study in the December 24/31 issue of JAMA.
Multiple micronutrient deficiencies are common among pregnant women in resource-poor regions of the world, especially in southern Asia. Coexisting with poor maternal nutrition across the region are excessive burdens of low birth weight (LBW), preterm birth, small size for gestational age, stillbirth, infant mortality, and maternal mortality. Gestational micronutrient deficiencies may contribute to avertable adverse birth outcomes. Data for effects of antenatal (before birth) multiple micronutrient (MM) supplementation on longer-term infant mortality are sparse for guiding policies in southern Asia, according to background information in the article.
Keith P. West Jr., Dr.P.H., of the Johns Hopkins Bloomberg School of Public Health, Baltimore, and colleagues conducted a study in which pregnant women in Bangladesh (n = 44,567) were randomly assigned to receive supplements containing 15 micronutrients or iron-folic acid alone, taken daily from early pregnancy to 12 weeks postpartum.
Among the 22,405 pregnancies in the multiple micronutrient group and the 22,162 pregnancies in the iron-folic acid group, there were 14,374 and 14,142 live-born infants, respectively, included in the analysis. At 6 months, multiple micronutrients did not significantly reduce infant mortality; there were 764 deaths (54.0 per 1,000 live births) in the iron-folic acid group and 741 deaths (51.6 per 1,000 live births) in the multiple micronutrient group.
Multiple micronutrient supplementation resulted in a non-statistically significant reduction in stillbirths (43.1 vs 48.2 per 1,000 births) and significant reductions in preterm births (18.6 vs 21.8 per 100 live births) and low birth weight (40.2 vs 45.7 per 100 live births).
“Our study’s null finding is in agreement with a small number of trials that have provided an antenatal multiple micronutrient vs iron supplement, with or without folic acid, and found no effect on neonatal mortality,” the authors write.
“Reasons for a null effect on postnatal survival after improvement in some birth outcomes with antenatal multiple micronutrient supplement use remain unknown but may reflect a complex interplay between maternal and newborn sizes and differential responses to supplementation by causes of death.”
The above story is based on materials provided by JAMA – Journal of the American Medical Association. Note: Materials may be edited for content and length.
NEVER-BEFORE-SEEN FOOTAGE walking you through my HOME GYM in Santa Monica, CA! SUBSCRIBE to my YouTube Channel HERE ▷ http://tonyhortonfitness.com/subscribe…
Now you can mount your favorite red sight or compact scope on the IZH-46M Air Pistol with the Air Venturi Weaver/Picatinny scope base rail! Features: Easy Installation 2 Allen Screws Secure The Base Weaver/Picatinny Rail Fits the Baikal IZH-46M Pistol
List Price: $ 19.99
Price: $ 19.99
Learn While Exercising Steel Frame 1 Padded Handle Rail 4 ABC Padded Spring Cover 3 Ages 3+ The Pure Fun Preschool Jumper is ideal for playing and learning. The ABC padded cover makes it fun to bounce while encouraging a child s alphabet, color and shape recognition. This trampoline is made to last with a steel frame, padded handle rail and springs, making it the perfect first trampoline. For age 3+ up to 75lbs. Product Specifications 36 L x 36 W x 33 Tall 2 Weight capacity: 75lbs
Price: $ 119.99
Sold by drugstore.com