2014/07/cd913_fitness_41n10kXhsHL._SL160_

Strategy proposed for preventing diseases of aging

Medicine focuses almost entirely on fighting chronic diseases in a piecemeal fashion as symptoms develop. Instead, more efforts should be directed to promoting interventions that have the potential to prevent multiple chronic diseases and extend healthy lifespans.

Researchers writing in the journal Nature say that by treating the metabolic and molecular causes of human aging, it may be possible to help people stay healthy into their 70s and 80s.

In a commentary published July 24 in Nature, a trio of aging experts calls for moving forward with preclinical and clinical strategies that have been shown to delay aging in animals. In addition to promoting a healthy diet and regular exercise, these strategies include slowing the metabolic and molecular causes of human aging, such as the incremental accumulation of cellular damage that occurs over time. The researchers, at Washington University School of Medicine in St. Louis, Brescia University in Italy, the Buck Institute for Aging and Research and the Longevity Institute at the University of Southern California, write that economic incentives in biomedical research and health care reward treating disease more than promoting good health.

“You don’t have to be a mathematician or an economist to understand that our current health care approach is not sustainable,” said first author Luigi Fontana, MD, PhD, professor of medicine and nutrition at Washington University and Brescia University. “As targeting diseases has helped people live longer, they are spending more years being sick with multiple disorders related to aging, and that’s expensive,” said

The diseases of old age — such as heart failure, diabetes, arthritis, cancer and Alzheimer’s disease — tend to come as a package, the researchers write. More than 70 percent of people over age 65 have two or more chronic diseases. But, they noted, studies of diet, genes and drugs indicate that interventions targeted to specific molecular pathways that delay one age-related disease often stave off others, too.

“Heart failure doesn’t happen all at once,” Fontana said. “It takes 30 or 40 years of an unhealthy lifestyle and activation of aging-related pathways from metabolic abnormalities such as high blood pressure, high cholesterol and type 2 diabetes to give a person heart failure in his 60s. So we propose using lifestyle interventions — such as a personalized healthy diet and exercise program — to down-regulate aging pathways so the patient avoids heart failure in the first place.”

His own research has highlighted potential benefits from dietary restriction in extending healthy life span. He has found that people who eat significantly fewer calories, while still getting optimal nutrition, have “younger,” more flexible hearts. They also have significantly lower blood pressure, much less inflammation in their bodies and their skeletal muscles function in ways similar to muscles in people who are significantly younger.

Fontana and his co-authors also point out that several molecular pathways shown to increase longevity in animals also are affected by approved and experimental

… Continue reading here.
Diet And Weight Loss News — Sciencedaily
— Courtesy “Science News Daily” (ScienceNewsDaily.com)

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Comments

    • Anastasia Huxley
    • July 24, 2014
    Reply

    You are awesome, love that you are “home schooled” ! I am new to pole
    fitness, gonna get a pole for home, what X-pole do you recommend ? I am
    your size. I want an x-pert stationary/spinning modes, but unsure if to
    get 45mm or 50mm. Your advice would be greatly appreciated !!! 

    View Comment
    • stacey klassen
    • July 24, 2014
    Reply

    woow this is really good,how long did it take you to be able to this stage?

    View Comment
    • Hannah S
    • July 24, 2014
    Reply

    Wow, you’re really good, awesome moves and great strength too :-)

    View Comment
    • Katja Saxbeck
    • July 24, 2014
    Reply

    Amazing…
    So talented!

    View Comment
    • Nutan Modha
    • July 24, 2014
    Reply

    For Matthew xx 

    View Comment
    • Anna Båve Schultz
    • July 24, 2014
    Reply

    Polefitness

    View Comment
    • William Andergren
    • July 24, 2014
    Reply

    Damn you’re good and i would say without hesitation you were a
    professional!
    Keep working girl! Big respect! <3

    View Comment
    • Heleen Rebecca
    • July 24, 2014
    Reply

    Beautiful and graceful! You make me wanne be as good as that. Just started
    this week. Full of bruises but love it. How long have you been doing this?

    View Comment
    • anaa1711
    • July 24, 2014
    Reply

    wooow girl you rock 🙂 how did you strengthen your arms like that? you are
    amazing :)

    View Comment
    • bunnypantsable
    • July 24, 2014
    Reply

    HOW

    View Comment
    • bunnypantsable
    • July 24, 2014
    Reply

    DAMN GURL

    View Comment
    • bunnypantsable
    • July 24, 2014
    Reply

    OMG TEACH ME OMG YOU ARE SO TINY AND PERFECT ILY

    View Comment
    • TheYazmanian
    • July 24, 2014
    Reply

    I haven’t seen anyone do this much variety of tricks before. You are a star
    in your own right.

    View Comment
    • M. Price
    • July 24, 2014
    Reply
    2 of 2 people found the following review helpful
    2.0 out of 5 stars
    Great until it popped 🙁, November 13, 2013
    By 
    M. Price
    (REAL NAME)
      

    Verified Purchase(What’s this?)
    This review is from: Fitness Ball: Silver, 30in/75cm Diameter, Includes 1 Ball +1 Pump + 1 Page Instruction Chart. No instructional DVD. (Exercise Gym Swiss Stability Ball) (Misc.)
    It was great until it popped. I was sitting on it and all of a sudden air was rushing out. It tore right at the stem. I need to send it back and get another one.

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    • Michael Turse
    • July 24, 2014
    Reply
    2 of 2 people found the following review helpful
    5.0 out of 5 stars
    Fantastic, November 18, 2013
    By 

    Verified Purchase(What’s this?)
    This review is from: Fitness Ball: Silver, 30in/75cm Diameter, Includes 1 Ball +1 Pump + 1 Page Instruction Chart. No instructional DVD. (Exercise Gym Swiss Stability Ball) (Misc.)
    GREAT PRODUCT. Variable sizes to fit your height. MUCH better and durable than any I’ve seen in stores. DON’T buy a “cheapie” GET THIS!!

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