2014/05/42e8f_fitness_416wmRP0-1L._SL160_

Disruption of circadian rhythms may contribute to inflammatory disease

A disruption of circadian rhythms, when combined with a high-fat, high-sugar diet, may contribute to inflammatory bowel disease and other harmful conditions, according to a recent study conducted by researchers at Rush University Medical Center. The study is online at the peer-reviewed, open-access journal, PLOS ONE.

“Circadian rhythms, which impose a 24-hour cycle on our bodies, are different from sleep patterns,” said Robin M. Voigt, PhD, assistant professor at Rush Medical College and first author of the study. “Sleep is a consequence of circadian rhythms,” Voigt said.

While circadian rhythm disruption may be common among some, the research suggests that it may be contributing to a host of diseases that may be prevented by regulating things such as sleep/wake patterns and times of eating to help prevent circadian rhythm disruption. Including prebiotics or probiotics in the diet can also help normalize the effects of circadian rhythm disruption on the intestinal microbiota to reduce the presence of inflammation.

“It’s something that needs to be addressed — not something people need to be very concerned about, but aware. If you have some of these other risk factors, like a high-fat, high-sugar diet,” or a genetic tendency toward disruption in circadian rhythms, “take precautions, watch your diet, take pre- and probiotics, monitor your health, be vigilant,” Voigt said.

The prevailing theory is that of a “second hit hypothesis” whereby individuals with at-risk lifestyle choices or genetic predispositions will only develop disease if a secondary insult is present. “We believe that chronic circadian rhythm disruption promotes/exacerbates inflammatory-mediated diseases, at least in part, due to changes in the intestinal microbiota,” she said.

Inflammation is associated with a number of diseases, including cardiovascular disease and cancer, and can cause organ damage and is associated with increased morbidity and mortality.

In the study, male mice had their cycles of exposure to light and dark reversed on a weekly basis (i.e., “shifted”), an experience that is known to disrupt an organism’s innate circadian rhythm. Some of the mice ate standard food; others ate a high-fat, high-sugar diet. Researchers found that the microbiota of the mice that had their circadian rhythms disrupted were significantly different from that of the control group — but only if they had consumed the high-fat, high-sugar diet.

All the mice that ate the high-fat, high-sugar diet displayed changes in the makeup of the microorganisms in their guts, regardless of circadian status. However, mice that ate the high-fat, high-sugar diet, and had circadian-rhythm disruptions, had higher concentrations of bacteria that are known to promote inflammation than any of the other mice in the study. Disrupting the circadian rhythms of the mice fed standard chow did not significantly affect the microbiota in their intestines.

These findings support previous studies that have shown that the negative effects of circadian disruption are subtle enough that “a second environmental insult is often

… Continue reading here.
Diet And Weight Loss News — Sciencedaily
— Courtesy “Science News Daily” (ScienceNewsDaily.com) <p>

CES 2014: Sony’s Smart Band Is Much More Than A Fitness Tracker. I got my hands-on with Sony’s upcoming Smart Band which will be launching later this year. C…

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Comments

    • BTechTalk
    • May 21, 2014
    Reply

    Sony is stepping up their game, excellent video Joel! :D

    View Comment
    • aztecadestructor1999
    • May 22, 2014
    Reply

    How much does it costs? 

    View Comment
    • Jan M
    • May 22, 2014
    Reply

    I really dont get the button, yeah it saves the moment but how? Does it not
    always safe your steps and calorie burns? So whats special about clicking
    the button, and why would I want to know what song I listened to then?

    View Comment
    • Chief Kief
    • May 22, 2014
    Reply

    enjoyed this one too

    View Comment
    • rsalas2006
    • May 22, 2014
    Reply

    i need one ¡¡¡

    View Comment
    • Brian Adair
    • May 22, 2014
    Reply

    Interesting 

    View Comment
    • Stampeding Zebras
    • May 22, 2014
    Reply

    Hey! I have the smart watch Pebble (heard of it?) I think its really good.
    Do any of these smart bands display info something like the Pebble?

    View Comment
    • J. Kincaid
    • May 22, 2014
    Reply
    21 of 21 people found the following review helpful
    3.0 out of 5 stars
    Mixed bag, September 17, 2013
    By 
    J. Kincaid (Portland, OR) –
    (REAL NAME)
      

    Verified Purchase(What’s this?)
    The ball itself is fine once you get it inflated, but the pump that comes with it is a cheap piece of junk. If you’re willing to spend a good 2 hours pumping, you’ll get it inflated eventually. There’s no valve of any kind in the actual ball, just a hole, so you have to be ready to get the plug in as soon as you remove the pump nozzle, and no matter how fast you’ll still lose a bunch of air. As others mentioned, the listing says the max capacity is 500 lbs, but the box says 250 lbs. The box also says it comes with a tool to pull the plug back out of the ball, but it doesn’t. Getting the plug back out the ball to inflate further is a chore, and you’ll end up with sore fingers and destroyed fingernails. The ball did inflate to the full 65 cm, eventually.

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    • A. Shultis "ABS869"
    • May 22, 2014
    Reply
    13 of 13 people found the following review helpful
    4.0 out of 5 stars
    great ball, crappy air pump, August 26, 2013
    By 

    Verified Purchase(What’s this?)
    Bought as a desk chair replacement. 75cm fits perfect with my long legs. According to my height (5’8″) I should have ordered a 65cm but I am glad I did not.

    Air pump provided did not work. Had to borrow someone else’s pump to fill. So far it’s holding it’s shape, hopefully I can borrow a pump again if I need to refill.

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