2014/04/578bc_workout_default

Higher muscle mass linked with better physical function, quality of life in dialysis patients

Dialysis patients with more muscle mass had better scores on a 6-minute walking test as well as better scores on physical and mental health questionnaires in a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). The findings suggest that physical activity that builds muscle mass may help improve the health and quality of life of dialysis patients.

Physical functional ability is often significantly impaired in patients on maintenance hemodialysis. Srinivasan Beddhu, MD (University of Utah), Macy Martinson, MD (University of Utah), T. Alp Ikizler (Vanderbilt University), and their colleagues wondered whether modifiable factors such as body size and body composition could influence dialysis patients’ physical function and quality of life.

To investigate, the researchers assessed 105 maintenance dialysis patients’ body mass index (BMI), waist circumference, and measurements of mid-thigh muscle area and intra-abdominal fat area. They also tested how far patients could walk in 6 minutes, and they examined other measures of physical and mental health through questionnaires. Assessments were made at the start of the study, after 6 months, and after 12 months.

The investigators found that higher BMI levels at the start of the study were linked with shorter 6-minute walking distances measured at both at the start of the study and at later time points. Results were similar for waist circumference and intra-abdominal fat. On the other hand, higher levels of mid-thigh muscle — which indicates higher muscle mass — were linked with longer 6-minute walking distances. After adjusting for BMI, increases in mid-thigh muscle were also strongly linked with higher physical and mental health scores at the start of the study, but only weakly so at later time points.

“Because this study shows that higher muscle mass is associated with better physical function and quality of life in dialysis patients, interventions such as increased physical activity that decrease fat mass and increase muscle mass are likely to improve physical function, quality of life, and survival in dialysis patients,” said Dr. Beddhu. “Such interventions need to be tested in clinical trials.”

The findings may help explain the “obesity paradox” associated with dialysis patients, which relates to the prolonged survival sometimes seen in obese patients compared with normal-weight patients. “The obesity paradox has been interpreted in earlier studies as fat is good. Some have even argued that weight loss should be discouraged in dialysis patients,” said Dr. Beddhu. “But the situation is more nuanced. This study provides a better understanding of the role of body composition in dialysis patients.”

Story Source:

The above story is based on materials provided by American Society of Nephrology (ASN). Note: Materials may be edited for content and length.

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Comments

    • Gloreebee1
    • April 26, 2014
    Reply

    Awesome!!!! Will do this workout soon as I wake up!!!

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    • fafoosnick6839
    • April 26, 2014
    Reply

    I’ve really enjoyed your workouts, Kelly and Daniel!! Keep ’em coming!

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    • nykia31
    • April 26, 2014
    Reply

    Ive become a fan of doing the 15-20 minute ones twice a day 3-4 times a
    week.. One 1st thing in the morning, the 2nd around 6pm. It just goes
    perfect with my day, and it is intense enough to feel like I got good work
    in. the other 2 days are more strength-endurance

    View Comment
    • Ashlee Fitz-Gerald
    • April 26, 2014
    Reply

    You guys should do more videos like this! It was so much fun and made the
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    • FitnessBlender
    • April 26, 2014
    Reply

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    • April 26, 2014
    Reply

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    • NaturallyBeingMe
    • April 26, 2014
    Reply

    Loved it!! It was quick and intense! I was super tired afterwards. Thanks
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    • April 26, 2014
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    Holy workout man! this was great!

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    • Amanda
    • April 26, 2014
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    Whew! That was a workout! Thanks for the vid :)

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    • MistressWe
    • April 26, 2014
    Reply

    i’m gonna do this in hal an hour with one of your 5 minutes warm up before
    and a posture workout after.

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    • ZippityD
    • April 26, 2014
    Reply

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    • Liz Mooney
    • April 26, 2014
    Reply

    these are great videos … thank you so much … not a gym by me that do
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    • Ivette G
    • April 26, 2014
    Reply

    I really love this! I do this when I can’t go run & it feels awesome :)

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    • kimberry2010
    • April 26, 2014
    Reply

    Love it. You guys are so adorable. Thank you for all that you do!

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    • Annie Tran
    • April 26, 2014
    Reply

    I love how you guys have the calorie counter on the side of your video! 

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    • April 26, 2014
    Reply

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    • April 26, 2014
    Reply

    You guys are the best, trying this today :D, thank you so much.

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    • عشق الورد
    • April 26, 2014
    Reply

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    • Yvonne R.
    • April 26, 2014
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    Thank you guys:))) I’m about to do this together with the standing ab
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    • Shruti B
    • April 26, 2014
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    Cuties!

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    • Paige K
    • April 26, 2014
    Reply

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    • April 26, 2014
    Reply

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    • Rebecca C
    • April 26, 2014
    Reply

    I loved this video! Thank you both for providing us with such great
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    • Irving Salinas
    • April 26, 2014
    Reply

    very good video, I’m subscribed now! 😉
    thanks!!!!

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    • debrawr
    • April 26, 2014
    Reply

    i love these workouts when you both are in them! it’s fun!!

    View Comment

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