2014/04/30e54_exercise_31vU88A3kwL._SL160_

Green is good: Natural compound from green tomatoes increases muscle, protects against muscle wasting

As unlikely as it sounds, green tomatoes may hold the answer to bigger, stronger muscles.

Using a screening method that previously identified a compound in apple peel as a muscle-boosting agent, a team of University of Iowa scientists has now discovered that tomatidine, a compound from green tomatoes, is even more potent for building muscle and protecting against muscle atrophy.

Muscle atrophy, or wasting, is caused by aging and a variety of illnesses and injuries, including cancer, heart failure, and orthopedic injuries, to name a few. It makes people weak and fatigued, impairs physical activity and quality of life, and predisposes people to falls and fractures. The condition affects more than 50 million Americans annually, including 30 million people over age 60, and often forces people into nursing homes or rehabilitation facilities.

“Muscle atrophy causes many problems for people, their families, and the health care system in general,” says Christopher Adams, M.D., Ph.D., UI associate professor of internal medicine and molecular physiology and biophysics. “However, we lack an effective way to prevent or treat it. Exercise certainly helps, but it’s not enough and not very possible for many people who are ill or injured.”

More muscle, less fat

In a new study, published online April 9 in the Journal of Biological Chemistry, Adams searched for a small molecule compound that might be used to treat muscle atrophy. He zeroed in on tomatidine using a systems biology tool called the Connectivity Map, which was developed at the Broad Institute of MIT and Harvard University. Adams discovered that tomatidine generates changes in gene expression that are essentially opposite to the changes that occur in muscle cells when people are affected by muscle atrophy.

After identifying tomatidine, Adams and his team tested its effects on skeletal muscle. They first discovered that tomatidine stimulates growth of cultured muscle cells from humans.

“That result was important because we are looking for something that can help people,” Adams says.

Their next step was to add tomatidine to the diet of mice. They found that healthy mice supplemented with tomatidine grew bigger muscles, became stronger and could exercise longer. And, most importantly, they found that tomatidine prevented and treated muscle atrophy.

Interestingly, although mice fed tomatidine had larger muscles, their overall body weight did not change due to a corresponding loss of fat, suggesting that the compound may also have potential for treating obesity.

Designing healthier foods

An attractive aspect of tomatidine is that it is a natural compound derived from tomatoes. It is produced when alpha-tomatine, which is found in tomato plants and in green tomatoes in particular, is digested in the gut.

“Green tomatoes are safe to eat in moderation. But we don’t know how many green tomatoes a person would need to eat to get a dose of tomatidine similar

… Continue reading here.
Fitness News — Sciencedaily
— Courtesy “Science News Daily” (ScienceNewsDaily.com) <p>

Solving chess puzzles and exercising your mental muscles By Mato Jelic.
Video Rating: 4 / 5

<p>[wpramazon asin=”B002VWK09Q”]

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Comments

    • Seth Glover
    • April 14, 2014
    Reply

    Thank you Mato I really need to buy your book
    http://www.amazon.com/Mato-Jelic/e/B00BEOEBTW !!!

    View Comment
    • Kieran Kaempen
    • April 14, 2014
    Reply

    I’m really not that bad at seeing these. The problems are:
    1. I always know there’s a good opportunity in these exercises, I don’t
    always know when there’s one in a game.
    2. Even if I could see these when they presented themselves in my games, I
    don’t know how to set them up to be executed. I can only really go for the
    obvious ones. 

    View Comment
    • Kevin Cousins
    • April 14, 2014
    Reply

    Wow I actually found most of them. 

    View Comment
    • nicolae calinescu
    • April 14, 2014
    Reply

    Thanks. Enjoy very much. Good exercise.

    View Comment
    • workdaypegasus
    • April 14, 2014
    Reply

    44 views 53 likes………
    Thanks for the video MatoJelic :)

    View Comment
    • Steven Zhou
    • April 14, 2014
    Reply

    so many queens died just for people to practice chess

    View Comment
    • Trias805
    • April 14, 2014
    Reply

    I couldn’t find 2 of them. I obviously considered queen sacrifices but
    couldn’t find good continuations.

    View Comment
    • Aaron Frawley
    • April 14, 2014
    Reply

    9 views 17 likes seems legit …

    View Comment
    • Nikola Jovanovic
    • April 14, 2014
    Reply

    This is too simple

    View Comment
    • MatoJelic
    • April 14, 2014
    Reply
    • Miko Tumag
    • April 14, 2014
    Reply

    the secret of chess is to find the impossible move at first look but in the
    combination end is a secret KILLER MOVE.

    View Comment
    • Jaqen H'gar
    • April 14, 2014
    Reply

    this is great and all . i guest most of them but the problem is they
    all have a pattern always queen sacrifice .
    it would be great if there is a variety of methods beside sacrificing ( the
    queen mostly ) 

    View Comment
    • André Mendonça Bastos
    • April 14, 2014
    Reply

    This was very easy ones because for me the queen’s sacrifices are implicity
    . Specially because your tips sometimes are a little annoying. Because they
    already solved the puzzle. But thanks for put it

    View Comment
    • Nikolay Belorusov
    • April 14, 2014
    Reply

    love you mato

    View Comment
    • Gilligan Escondito
    • April 14, 2014
    Reply

    Does anyone else always see all of these immediately? It’s always
    impossible for me to find these moves in blitz though

    View Comment
    • mesonparticle
    • April 14, 2014
    Reply

    Always love Mato’s “Vot vould you do?” 🙂 <3

    View Comment
    • Jahanam9994
    • April 14, 2014
    Reply

    I missed three of them, one because I misinterpreted the order in which I
    should play my moves. My main problem is I can see the individual good
    moves, but can’t always string them together for the checkmate.

    View Comment
    • Yan Khonskiy
    • April 14, 2014
    Reply

    Thank you, Mato. Tactics is important. Endgames and openings are crucial
    too. It is a good idea to make exercise videos here. I’d like to improve my
    endgame skills too. I’m still bad at endgames, even an equal position be
    lost for me. 

    View Comment
    • Izik Bargil
    • April 14, 2014
    Reply

    TOO EASY

    View Comment
    • Ronald Sebastiane
    • April 14, 2014
    Reply

    i had managed to solve most of it;however, because you told that there is
    an opportunity to call checkmate, i found it but how can i know in a middle
    of a game?

    View Comment
    • Parthapratim Mali
    • April 14, 2014
    Reply

    in the 3rd one i can save the black king.. just use black bishop to take
    the white rook in the first move.. 

    View Comment
    • Baltix Hook
    • April 14, 2014
    Reply

    great video :)

    View Comment
    • Mickael Czarny
    • April 14, 2014
    Reply

    thank you!

    View Comment
    • N. Nkenge
    • April 14, 2014
    Reply
    116 of 124 people found the following review helpful
    5.0 out of 5 stars
    Great exercise choice for sedentary or obese people, August 22, 2009
    By 
    N. Nkenge (New York) –
    (REAL NAME)
      

    Amazon Verified Purchase(What’s this?)
    I was inspired to purchase a pedal exerciser because of the savings it offers from the more costly stationary bike and because it is a viable fitness option for people like me who are sedentary and obese. I have been using my pedals since they day they arrived by mail and love the fact that they come fully assembled, are cost-effective and compact enough to store without dedicated storage space. There are no excuses to everyday movement with this in your household! It is worth the investment and combined with the use of free weights, provides a full body workout experience. The only drawback is that it should not be touched-moved immediately following a workout because it does generate extreme heat and it also shifts around too much to be used on hardwood floors so it is most conducive to the carpeted areas of your home.

    0

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    • Margaret Daum
    • April 14, 2014
    Reply
    115 of 123 people found the following review helpful
    5.0 out of 5 stars
    Excellent Reconditioning for Everyone, August 26, 2009
    By 

    I am a licensed physical therapist asst and I purchased 10 on these bikes at a very affordable cost. I went to many websites, even E-bay
    and could not get this item for less that $27.00; I haggled and haggled
    with this guy and he simply would not work with me. Then I went to Amazon.com and there she was! This bike has adjustable resistance to strengthen both arms and legs; it is great for endurance traning and
    for gaining AROM post knee surgery(PROVIDED MD ENDORSES IT). Personally,
    I purchased in bulk for my patients upon Discharge from therapy. I did
    not want to pull out unless I was sure they were able to maintain or increase the progress they had made. It is an excellent investment for
    anyone; you can put it on the floor for legs or on table for arms and you
    can pedal away while you watch your favorite TV programs, work a crossword puzzle, knit, or whatever is your “thing”. Because Medicare will not pay for it and I assure you the cost out of pocket is more than
    reasonable, I would recommend this bike highly for anyone!(If however,
    you are diagnosed with a certain condition you must consult with your MD
    about using it, especially those with cardiac precautions.) I give it a 10++.

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