Metformin, a generic of Glucophage, is used in the treatment of diabetes to help diabetics lose weight. The function of Glucophage is to reduce sugar release levels in the liver, preventing the level of blood glucose from becoming elevated, which results in less insulin being produced by the body. Too much insulin in the bloodstream acts on the brain, causing feelings of hunger, which is satisfied by eating, and the diabetic gains weight. Metformin helps with weight loss by lowering the appetite and preventing blood sugar levels from rising too high.
Metformin and Weight Loss
Metformin is used successfully to lower blood glucose levels and prevent weight gain in Type 2 diabetics, combined with a healthy diet and a reduction in foods that will elevate blood sugar levels, like refined sugars and saturated fats. The recommended dosage is 500mg before meals.
However, Metformin has also been proven to be effective for weight reduction in non-diabetics. In a recent study at Stanford, it was found that Metformin significantly decreased the body mass indices of obese adolescents who were non-diabetic and also noted improved insulin resistance. Since childhood obesity and overweight afflicts more than 1/3 of children in the U.S., Metformin could prove to be an important breakthrough in the continual child obesity battle.
Although it has long been accepted that Metformin